Molecular and Systems Biotechnology Lab @ UIUC

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Peer-reviewed articles


  • Oh, E., Skerker, J.M., Kim, S.R., Wei, N., Turner, T.L., Maurer, M., Arkin, A.P., Jin, Y.S. Gene amplification on demand accelerates cellobiose utilization in engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology (in press)
  • Xia, P., Zhang, G.C., Liu, J., Kwak, S., Tsai, C.S., Kong, I.I., Sung, B.H., Sohn, J.H., Wang, S.G., Jin, Y.S. GroE chaperonins assisted functional expression of bacterial enzymes in Saccharomyces cerevisiae. Biotechnology and Bioengineering (in press)
  • Liu, J., Kong, I.I., Zhang, G., Jayakody, L., Kim, H., Xia, P.F., Kwak, S., Sung, B.H., Sohn, J.H., Walukiewicz, H., Rao, C., Jin, Y.S. Metabolic engineering of a probiotic Saccharomyces boulardii. Applied and Environmental Microbiology (in press)
  • Lia, X., Parka, A., Estrelaa, R., Kim, S.R., Jin, Y.S., Cate, J.H.D. Comparison of xylose fermentation by two high-performance engineered strains of Saccharomyces cerevisiae. Biotechnology Reports (in press)
  • Kim, J.S., Cho, D.H., Heo, P., Jung, S.C., Park, M., Oh, E.J., Sung, J., Kim, P.J., Lee, S., Lee, D., Lee, S., Lee, C.H., Shin, D., Jin, Y.S., Kweon, D.H. Fumarate-mediated persistence of Escherichia coli against antibiotics. Antimicrobial Agents and Chemotherapy (in press)


  • Xu, H., Kim, S., Sorek, H., Lee, Y., Jeong, D., Kim, J.Y., Oh, E.J., Yun, E.J., Wemmer, D.E., Kim, K.H., Jin, Y.S., Kim, S.R. (2015), PHO13 Deletion-Induced Transcriptional Activation Prevents Sedoheptulose Accumulation during Xylose Metabolism in Engineered Saccharomyces cerevisiae. Metabolic Engineering (Accepted)
  • Jayakody, L.N., Lane, S., Kim, H., Jin, Y.S. (2015), Mitigating health risks associated with alcoholic beverages through metabolic engineering. Current Opinions in Biotechnology (In press)
  • Park, Y.C., Oh, E.J., Jo, J.H., Jin, Y.S., Seo, J.H. (2015) Recent advances in biological production of sugar alcohols. Current Opinions in Biotechnology (In press)
  • Zhang, G.C., Liu, J.J., Kong, I.I., Kwak, S., Jin, Y.S. (2015), Combining C6 and C5 sugar metabolism for enhancing microbial bioconversion. Current Opinions in Chemical Biology (In press)
  • Turner, T.L., Zhang, G.-C., Oh, E.J., Subramaniam, V., Adiputra, A., Subramaniam, V., Skory, C.D., Jang, J.Y., Yu, B.J., Park, I. and Jin, Y.-S. (2015), Lactic acid production from cellobiose and xylose by engineered Saccharomyces cerevisiae. Biotechnololgy and Bioengineering Link (In press)
  • Yun, E.J., Kwak, S., Kim, S.R., Park, Y.C., Jin, Y.S., Kim, K. H. Production of (S)-3-hydroxyburate by metabolically engineered Saccharomyces cerevisiae. Journal of Biotechnology 209 (2015): 23-30. Link
  • Liao, C., Seo, S.O., Celik, V., Liu, H., Kong, W., Wang, Y., Blaschek, H., Jin, Y.S., Lu, T. Integrated, systems metabolic picture of the acetone-butanol-ethanol fermentation by Clostridium acetobutylicum. Proceedings of the National Academy of Sciences 112.27 (2015): 8505-8510. Link
  • Turner, T.L., Zhang, G.C., Kim, S.R., Subramaniam, V., Steffen, D., Skory, C.D., Jang, J.Y., Yu, B.J., Jin, Y.S. Lactic acid production from xylose by engineered Saccharomyces cerevisiae without PDC or ADH deletion. Applied Microbiology and Biotechnology 99.19 (2015): 8023-8033. Link
  • Tsai, C.S., Kong, I.I., Lesmana, A., Million, G., Zhang, G.C., Kim, S.R., Jin, Y.S. Rapid and marker-free Cas9/CRISPR refactoring yields equivalent xylose-utilization performance in yeast. Biotechnology and Bioengineering 112 (2015): 2406–2411. doi:10.1002/bit.25632 Link
  • Kim, S., Sung, J., Foo, M., Jin, Y.S., Kim, P.J. Uncovering the nutritional landscape of food. Plos One 10(4), e0118697 Link
  • Kim, J.W., Seo, S.O., Zhang, G.C., Jin, Y.S., Seo, J.H. Expression of Lactococcus lactis NADH oxidase increases 2,3-butanediol production in Pdc-deficient Saccharomyces cerevisiae. Bioresource Technology 191 (2015): 512-519. Link
  • Kim, S.K., Jin, Y.S., Cho,I.G., Park, Y.C., Seo, J.H. Enhanced tolerance of Saccharomyces cerevisiae to multiple lignocellulose-derived inhibitors through modulation of spermidine contents. Metabolic Engineering 29 (2015): 46-55. Link
  • Kim, S.M., Guo, J., Kwak, S., Jn, Y.S., Lee, D.K., Singh, V. Effects of genetic variation and growing condition of Prairie Cordgrass on feedstock composition and ethanol yield. Bioresource Technology 183 (2015): 70-77. Link
  • Li, X., Vivian, Y.Y., Lin, Y., Chomvong, K., Estrela, R., Liang, J.M., Znameroski, E.A., Feehan, J., Kim, S.R., Jin, Y.S., Glass, N.L., Cate, J.H.D. Expanding xylose metabolism in yeast for plant cell wall conversion to biofuels. eLife 2015 Feb 3;4. doi: 10.7554/eLife.05896.Link
  • Lewis, Z.T., Totten, S.M., Smilowitz, J.T., Popovic, M., Parker, E., Lemay, D.G., Van Tassell, M.L., Miller, M.J., Jin, Y.S., German, J.B., Lebrilla, C.B., Mills, D.A. Maternal Fucosyltransferase 2 Status Affects the Gut Bifidobacterial Communities of Breastfed Infants. Microbiome 10;3:13. doi: 10.1186/s40168-015-0071-z. eCollection 2015 Link
  • Yi, W., Zhang, X., Seo, S., Choi, K., Ting, L., Jin, Y.S., Hans, B. Markerless chromosomal gene deletion in Clostridium beijerinckii using CRISPR/Cas9 system. Journal of Biotechnology 200 (2015): 1-5. Link
  • Wei, N., Oh, E.J., Million, G., Cate, J., Jin, Y.S. Simultaneous utilization of cellobiose, xylose, and acetic acid from lignocellulosic biomass for biofuel production by an engineered yeast platform. ACS Synthetic Biology 4(6), 707-713. Link


  • Kim, S.R., Xu, H., Lesmana, A., Kuzmanovic, U., Au, M., Florencia, C., Oh, E.J., Zhang, G., Kim, H.K., and Jin, Y.S. Deletion of PHO13 encoding HAD type IIA phosphatase results in upregulation of the pentose phosphate pathway in yeast. Applied and Environmental Microbiology 81(5):1601-9. doi: 10.1128/AEM.03474-14. Link
  • Quarterman, J., Kim, S.R., Kim, P.J., Jin, Y.S. Enhanced hexose fermentation by Saccharomyces cerevisiae through integration of stoichiometric modeling and genetic screening. Journal of Biotechnology Link
  • Kim, T. Y., Oh, E. J., Jin, Y. S., Oh, M. K. Improved resistance against oxidative stress of engineered cellobiose-fermenting Saccharomyces cerevisiae revealed by metabolite profiling. Biotechnology and Bioprocess Engineering, 19(6), 951-957. Link
  • Lane, S., Zhang, S., Wei, N., Rao, C., Jin, Y.S. Development and Physiological Characterization of Cellobiose-Consuming Yarrowia lipolytica. Biotechnology & Bioengineering 112(5):1012-22. doi: 10.1002/bit.25499. Link
  • Zhang, G., Kong, I.I., Kim, H., Liu, J., Cate, J.H.D., Jin, Y.S. Construction of a quadruple auxotrophic mutant of an industrial polyploidy Saccharomyces cerevisiae using RNA-guided Cas9 nuclease. Applied and Environmental Microbiology Link
  • Tsai, C.S., Kwak, S., Turner, T.L., Jin, Y.S. Yeast synthetic biology toolbox and applications for biofuel production. FEMS Yeast Research doi: 10.1111/1567-1364.12206. Link
  • Lin, Y., Chomvong, L., Acosta-Sampson, L., Estrela, R., Galazka, J.M., Kim, S.R., Jin, Y.S., Cate, J.H.D. Leveraging transcription factors to speed cellobiose fermentation by Saccharomyces cerevisiae. Biotechnology for Biofuels Link
  • Chomvong, K., Kordic, V., Li, X., Bauer, S., Gillespie. A.E., Ha, S.J., Oh, E.J., Galazka, J.M., Jin, Y.S., Cate, J.H. Overcoming inefficient cellobiose fermentation by cellobiose phosphorylase in the presence of xylose. Biotechnology for Biofuels Link
  • Hong, N., Seo, S.S., Oh, E.J., Seo, J.H., Cate, J.H., Jin, Y.S. 2,3-Butanediol production from cellobiose by engineered Saccharomyces cerevisiae. Applied Microbiology and Biotechnology Link
  • Kim, S.J., Seo, S.O., Park, Y.C., Jin, Y.S., Seo, J.H. Production of 2,3-Butanediol from xylose by engineered Saccharomyces cerevisiae. Journal of Biotechnology Link


  • Bae, Y.H., Kang, K.H., Jin, Y.S., Seo, J.H. Molecular cloning and expression of fungal cellobiose transporters and β-glucosidases conferring efficient cellobiose fermentation in Saccharomyces cerevisiae. Journal of Biotechnology, 169, 34-41 Link
  • Kim, H., Lee, W.H., Galazka, J.M., Cate, J.H., Jin, Y.S. Analysis of cellodextrin transporters from Neurospora crassa in Saccharomyces cerevisiae for cellobiose fermentation. Applied Microbiology and Biotechnology, 1-8 Link
  • Ha, S.J., Kim, S.R., Kim, H., Du, J., Cate, J.H., Jin, Y.S. Continuous co-fermentation of cellobiose and xylose by engineered Saccharomyces cerevisiae. Bioresource Technology, 149, 525-531 Link
  • Li, S., Ha, S.J., Kim, H.J., Galazka, J.M., Cate, J.H., Jin, Y.S., Zhao, H. Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization. Journal of Biotechnology 168, 1-6. Link
  • Kim, H.J., Lee, H.R., Kim, C.S., Jin, Y.S., Seo, J.H. Investigation of protein expression profiles of erythritol-producing Candida magnoliae in response to glucose perturbation. Enzyme and Microbial Technology 53, 174-180 Link
  • Kim, H.J., Turner, T.L., Jin, Y.S. Combinatorial genetic perturbation to refince metabolic circuits for producing biofuels and biochemicals. Biotechnology Advances 31, 976-985 Link
  • Kim, S.J., Seo, S.O., Jin, Y.S., Seo, J.H. Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresource Technology 146, 274-281 Link
  • Wang, Y., Li, X.Z., Milne, C., Janssen, H., Lin, W., Phan, G., Hu, H., Jin, Y.S., Price, N., Blaschek, H. Development of a gene knockout system using mobile group II introns (Targetron) and genetic disruption of acid production pathways in Clostridium beijerinckii. Applied and Environmental Microbiology 79, 5853-5863 Link
  • Lee, W.H., Nan, H., Kim, H.J., Jin, Y.S. Simultaneous saccharification and fermentation by engineered Saccharomyces cerevisiae without supplementing extracellular beta-glucosidase. Journal of Biotechnology 167, 316-322 Link
  • Kim, S.R., Park, Y.C., Jin, Y.S., Seo, J.H. Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism. Biotechnology Advances 31, 851-861 Link
  • Wei, N., Xu, H., Kim, S.R., & Jin, Y.S. Deletion of FPS1 coding for aquaglyceroporin Fps1p improves xylose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology Link
  • Kim, S.R., Kwee, N.R., Kim, H.J. & Jin, Y.S. Feasibility of xylose fermentation by engineered Saccharomyces cerevisiae overexpressing endogenous aldose reductase (GRE3), xylitol dehydrogenase (XYL2) and xylulokinase (XYL3) from Scheffersomyces stipitis. FEMS Yeast Research Link
  • Lee, W.H., Kim, M.D., Jin, Y.S. & Seo, J.H. Engineering of NADPH regenerators in Escherichia coli for enhanced biotransformation. Applied Microbiology and Biotechnology Link
  • Kim, S.R., Skerker, J.M., Kang, W., Lesmana, A., Wei, N., Arkin, A.P. & Jin, Y.S. Rational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in Saccharomyces cerevisiae. PLOS One Link
  • Kim, S.R., Lee, K.S., Kong, I.K., Lesmana, A., Lee, W.H., Seo, J.H., Kweon, D.H. & Jin, Y.S. Construction of an efficient xylose-fermenting diploid Saccharomyces cerevisiae strain through mating of two engineered haploid strains capable of xylose assimilation. Journal of Biotechnology Link


  • Guo, B., Zhang, Y., Yu, G., Lee, W.H., Jin, Y.S.& Morgenroth, E., Two-stage acidic-alkaline hydrothermal pretreatment of lignocellulose for the high recovery of cellulose and hemicellulose sugars. Applied Biochemistry and Biotechnology Link
  • Ha,S.J., Kim, H., Lin, Y., Jang, M.U., Galazka, J.M., Kim, T.J., Cate. J.H. & Jin, Y.S. Single amino acid substitutions of HXT2.4 from Scheffersomyces stipitis lead to improved cellobiose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology Link
  • Ha, S.J., Galazka, J.M., Oh, E.J., Kordic, V., Kim, H., Jin, Y.S., & Cate, J.H. Energetic benefits and rapid cellobiose fermentation by Saccharomyces cerevisiae expressing cellobiose phosphorylase and mutant cellodextrin transporters. Metabolic Engineering Link
  • Wei, N. Quarterman, J., & Jin, Y.S. Marine macroalgae: an untapped resource for producing fuels and chemicals. Trends in Biotechnol. Link
  • Oh, E.J., Ha, S.J., Kim, S.R., Lee, W.H., Galazka, J.M., Cate, J.H. & Jin, Y.S. Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered Saccharomyces cerevisiae. Metabolic Engineering Link
  • Lee, K.S., Kim, J.S., Heo, P., Yang, T.J., Sung, Y.J., Cheon, Y., Koo, H.M., Yu, B.J., Seo, J.H., Jin, Y.S., Park, J.C., Kweon, D.H. Characterization of Saccharomyces cerevisiae promoters for heterologous gene expression in Kluyveromyces marxianus. Appl Microbiol Biotechnol Link
  • Lee, W.H., Pathanibul, P., Quarterman, J., Jo, J.H., Han, N.S., Miller, M.J., Jin, Y.S.& Seo, J.H. Whole cell biosynthesis of a functional oligosaccharide, 2-fucosyllactose, using engineered Escherichia coli. Microbial Cell Factories 11, 48 Link
  • Lee, W.H., Seo, S.O., Bae, Y.H., Nan, H., Jin, Y.S.& Seo, J.H. Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess and Biosystems Engineering 35, 1467-75 Link
  • Kim, S.R., Ha, S.J., Kong, I.I., & Jin, Y.S. High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae Metab. Eng. 14, 336-343 Link
  • Guo, B., Zhang, Y., Ha, S. J., Jin, Y.S.& Morgenroth, E. Combined biomimetic and inorganic acids hydrolysis of hemicellulose in Miscanthus for bioethanol production. Bioresource Technol 110,278-87 Link
  • Kim, S.R., Ha, S.J., Wei, N., Oh, E.J., & Jin, Y.S. Simultaneous co-fermenation of mixed sugars: a promising strategy for producing cellulosic ethnaol. Trend Biotechnol 30,274–282 Link
  • Jin, Y.S. & Cate, J.H. Model-guided strain improvement: Simultaneous hydrolysis and co-fermentation of cellulosic sugars. Biotechnol. J. 7,361-73. Link
  • Cha, C., Kim, S.R., Jin, Y.S. & Kong, H.J. Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production. Biotechnol. Bioeng. 109,63-73 Link


  • Lu, C.H., Choi, J.H., Engelmann Moran, N., Jin, Y.S. & Erdman, J. Laboratory-scale production of 13C-labeled lycopene and phytoene by bioengineered Escherichia. J Agric Food Chem Link
  • Kim, J.S., Heo P., Yang. T.J., Lee, K.S., Jin Y.S., Kim, S. K., Shin, D. & Kweon, D.H. Bacterial persisters tolerate antibiotics by not producing hydroxyl radicals. Biochem. Biophys. Res. Commun. Link
  • Milne, C.B., Eddy, J.A., Raju, R., Ardekani,S., Kim, P.J., Senger, R. S., Jin, Y.S., Blaschek, H.P. & Price, N.D. Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052 BMC Systems Biology 5:130. Link
  • Ha, S.J., Wei, Q., Kim, S.R., Galazka, J., Cate, J.H. & Jin, Y.S. Co-fermentation of cellobiose and galactose by an engineered Saccharomyces cerevisiae. Appl. Environ. Microbiol. 77, 5822-5826. Link, Related News
  • Ha, S.J., Kim, S.R., Choi J.H., Park, M.S. & Jin Y.S. Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitro. Appl Microbiol Biotechnol Link
  • Ha, S.J., Galazka J.M., Rin Kim S., Choi J.H., Yang X., Seo J.H., Louise Glass N., Cate J.H., & Jin Y.S.Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proc Natl Acad Sci U S A. 108, 504-509 (2011) Link,In This Issue-PNAS, Related News
  • Lee, K.S., Hong, M.E., Jung, S.C., Ha, S.J., Yu, B.J., Koo, H.M., Park, S.M., Seo, J.H., Kweon, D.H., Park, J.C. & Jin, Y.S. Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering. Biotechnol Bioeng. 108, 621-632. Link


  • Kim, S.R., Lee, K.S., Choi, J.H., Ha, S.J., Kweon, D.H., Seo, J.H. & Jin, Y.S. Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient Saccharomyces cerevisiae engineered for xylose metabolism. J Biotechnol 150, 404-407 (2010). Link
  • Jung, S.C., Smith, C.L., Lee, K.S., Hong, M.E., Kweon, D.H., Stephanopoulos, G. & Jin, Y.S. Restoration of growth phenotypes of Escherichia coli DH5alpha in minimal media through reversal of a point mutation in purB. Appl Environ Microbiol 76, 6307-6309 (2010). Link, Related News1, Related News2
  • Hong, M.E., Lee, K.S., Yu, B.J., Sung, Y.J., Park, S.M., Koo, H.M., Kweon, D.H., Park, J.C. & Jin, Y.S. Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. J Biotechnol 149, 52-59 (2010). Link, Related News


  • Tyo, K.E., Jin, Y.S., Espinoza, F.A. & Stephanopoulos, G. Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803. Biotechnol Prog 25, 1236-1243 (2009). Link
  • Shin, J.Y., Shin, J.I., Kim, J.S., Yang, Y.S., Hwang, Y., Yang, J.S., Shin, D., Seo, J.H., Jin, Y.S., Park, Y.C., Hwang, J.S. & Kweon, D.H. Assembly of Coenzyme Q10 nanostructure resembling nascent discoidal high density lipoprotein particle. Biochem Biophys Res Commun 388, 217-221 (2009). Link
  • Lee, K., Shin, J.Y., Yang, Y.S., Shin, J.I., Park, Y.C., Seo, J.H., Park, T.H., Shin, C.S., Jin, Y.S. & Kweon, D.H. Towards a microarray of functional membrane proteins: Assembly of a surface-attachable, membrane-protein-anchored membrane structure using apolipoprotein A-1. Enz. Microb Tech 44, 217-222 (2009). Link
  • Lee, J., Seo, E., Kweon, D.H., Park, K. & Jin, Y.S. Fermentation of rice bran and defatted rice rran for butanol production using Clostridium beijerinckii NCIMB 8052. J. Microbiol. Biotechnol. 19, 482-490 (2009). Link


  • Lee, K.S., Chang, E.H., Shin, J.Y., Kweon, D.H., Park, K.M. & Jin, Y.S. Production of casein phosphopeptides using Streptococcus faecalis var. liquefaciens cell immobilization. Korean J Biotechnol Bioeng 23, 59-64 (2008). Link
  • Jung, C.H., Yang, Y.S., Kim, J.S., Shin, J.I., Jin, Y.S., Shin, J.Y., Lee, J.H., Chung, K.M., Hwang, J.S., Oh, J.M., Shin, Y.K. & Kweon, D.H. A search for synthetic peptides that inhibit soluble N-ethylmaleimide sensitive-factor attachment receptor-mediated membrane fusion. FEBS J 275, 3051-3063 (2008). Link


  • Jung, S.C., Chung, C.Y., Kim, J.S., Kweon, D.H., Park, K.M. & Jin, Y.S. Policosanol production from rice bran oil byproducts. Food Eng Prog 11, 293-297 (2007) Link
  • Jin, Y.S. & Stephanopoulos, G. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab Eng 9, 337-347 (2007). Link
  • Jeffries, T.W., Grigoriev, I.V., Grimwood, J., Laplaza, J.M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y.S., Passoth, V. & Richardson, P.M. Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Nat Biotechnol 25, 319-326 (2007). Link
  • Laplaza, J.M., Torres, B.R., Jin, Y.S. & Jeffries, T.W. Sh ble and Cre adapted for functional genomics and metabolic engineering of Pichia stipitis. Enz Microb Tech 38, 741-747 (2006). Link
  • Jin, Y.S., Cruz, J. & Jeffries, T.W. Xylitol production by a Pichia stipitis D-xylulokinase mutant. Appl Microbiol Biotechnol 68, 42-45 (2005). Link
  • Jin, Y.S., Alper, H., Yang, Y.T. & Stephanopoulos, G. Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Appl Environ Microbiol 71, 8249-8256 (2005). Link
  • Alper, H., Jin, Y.S., Moxley, J.F. & Stephanopoulos, G. Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metab Eng 7, 155-164 (2005). Link
  • Jin, Y.S., Laplaza, J.M. & Jeffries, T.W. Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response. Appl Environ Microbiol 70, 6816-6825 (2004). Link
  • Jin, Y.S. & Jeffries, T.W. Stoichiometric network constraints on xylose metabolism by recombinant Saccharomyces cerevisiae. Metab Eng 6, 229-238 (2004). Link
  • Jeffries, T.W. & Jin, Y.S. Metabolic engineering for improved fermentation of pentoses by yeasts. Appl Microbiol Biotechnol 63, 495-509 (2004). Link
  • Jin, Y.S., Ni, H., Laplaza, J.M. & Jeffries, T.W. Optimal growth and ethanol production from xylose by recombinant Saccharomyces cerevisiae require moderate D-xylulokinase activity. Appl Environ Microbiol 69, 495-503 (2003). Link
  • Jin, Y.S. & Jeffries, T.W. Changing flux of xylose metabolites by altering expression of xylose reductase and xylitol dehydrogenase in recombinant Saccharomyces cerevisiae. Appl Biochem Biotechnol 105 -108, 277-286 (2003). Link
  • Jin, Y.S., Jones, S., Shi, N.Q. & Jeffries, T.W. Molecular cloning of XYL3 (D-xylulokinase) from Pichia stipitis and characterization of its physiological function. Appl Environ Microbiol 68, 1232-1239 (2002). Link
  • Jin, Y.S., Lee, T.H., Choi, Y.D., Ryu, Y.W. & Seo, J.H. Conversion of xylose to ethanol by recombinant Saccharomyces cerevisiae containing genes for xylose reductase and xylitol dehydrogenase from Pichia stipitis. J Microbiol Biotechnol 10, 564-567 (2000). Link
  • Jeffries, T.W. & Jin, Y.S. Ethanol and thermotolerance in the bioconversion of xylose by yeasts. Adv Appl Microbiol 47, 221-268 (2000). Link